N-Acetyl PT-141

Overview

N-Acetyl PT-141 is a modified analog of the synthetic peptide PT-141 (bremelanotide). It belongs to a class of peptides derived from α-melanocyte-stimulating hormone (α-MSH). It is commonly investigated in biochemical research focusing on melanocortin receptor signaling pathways.

The N-acetyl modification is applied to boost peptide stability and molecular handling in laboratory environments. Because of its structural relationship with melanocortin receptor ligands, the compound is frequently examined in receptor-binding and molecular signaling research models.

N-Acetyl PT-141 is supplied strictly as a research compound intended for controlled laboratory investigation.

N-Acetyl PT-141

Property	Description
Compound Name	N-Acetyl PT-141
Parent Compound	PT-141 (Bremelanotide)
Peptide Class	Melanocortin receptor agonist analog
Molecular Type	Synthetic peptide
Structural Origin	α-melanocyte-stimulating hormone (α-MSH) analog
Research Category	Peptide signaling research compound

Mechanism of Action

Melanocortin Receptor Interaction

N-Acetyl PT-141 is investigated for its interaction with melanocortin receptor subtypes. This is mostly done in receptors associated with melanocortin signaling pathways. These receptors belong to the G-protein-coupled receptor (GPCR) family, which participates in intracellular signaling cascades within experimental systems.

Peptide Signaling Pathway Studies

Because of its structural relationship to melanocortin peptides, the compound may be examined in receptor-ligand binding assays designed to evaluate peptide-mediated signaling mechanisms. Laboratory investigations often focus on how synthetic analogs influence intracellular signaling events and receptor activation patterns.

Structure-Activity Relationship Research

Synthetic analogs such as N-Acetyl PT-141 are frequently used in structure-activity relationship (SAR) studies. These investigations examine how chemical modifications to peptide structures influence receptor affinity, molecular stability, and ligand-binding dynamics.

Research Applications

In controlled laboratory settings, N-Acetyl PT-141 may be utilized for investigations involving:

• melanocortin receptor interaction assays
• peptide-receptor binding studies
• molecular signaling pathway analysis involving GPCR systems
• structure-activity relationship investigations of melanocortin analogs
• analytical characterization of synthetic peptide compounds

All applications are restricted strictly to analytical and experimental research environments.

Why Choose Purerawz?

Buy N-Acetyl PT-141 for laboratory research use from our online shop. At Purerawz, we provide high-quality reference materials intended strictly for research purposes. Each compound is supplied with an independent third-party Certificate of Analysis verifying identity, purity, and concentration.

Note: N-Acetyl PT-141 is an investigational compound currently undergoing scientific evaluation and has not been established as safe or effective for any therapeutic application.

Disclaimer

This information is for educational purposes only and does not constitute medical advice.

THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the Institutional Animal Care and Use Committee (IACUC) in accordance with the guidelines of the Animal Welfare Act (AWA).

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ATTENTION: All products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use.

References

Molinoff, P. B., Shadiack, A. M., Earle, D., Diamond, L. E., & Quon, C. Y. (2003).
PT-141: a melanocortin agonist for the treatment. Annals of the New York Academy of Sciences. PubMed: https://pubmed.ncbi.nlm.nih.gov/12851303/

Diamond, L. E., Earle, D. C., Rosen, R. C., Willett, M. S., & Molinoff, P. B. (2004).
Double-blind, placebo-controlled evaluation of intranasal PT-141, a melanocortin receptor agonist. International Journal of Impotence Research. PubMed: https://pubmed.ncbi.nlm.nih.gov/14963471/

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All products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use.