ACP 105

ACP 105 Overview

ACP-105 is a non-steroidal compound investigated in scientific literature as a selective androgen receptor modulator (SARM). Structurally and functionally, it has been studied for its ability to interact with androgen receptors in experimental models.

In preclinical investigations, ACP-105 has demonstrated partial agonist activity at androgen receptors, indicating its potential to selectively influence androgen receptor signaling pathways under controlled laboratory conditions. Early experimental studies have explored its interaction with skeletal muscle, bone tissue, and other androgen-responsive systems in animal models.

Chemical and Molecular Properties

PubChem CID	11638442
Molecular Formula	C16H19ClN2O
Molecular Weight	290.79 g/mol
Synonyms	[4-(5-hydroxy-2-methyl-1-benzofuran-3-yl)oxy-2-methyl-2-(methylsulfonyl)butanenitrile] (Chemical Name) 10-hydroxy-2-methyl-2-(methylsulfonyl)-4-(2-methyl-1-benzofuran-5-yl)oxybutanenitrile (Alternative IUPAC) 2-(Methylsulfonyl)-4-(2-methyl-1-benzofuran-5-yloxy)-2-methylbutanenitrile
IUPAC	2-Chloro-4-[(1R,5R)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octan-8-yl]-3-methylbenzonitrile
CAS	899821-23-9
Labeling	Research Use Only (RUO), not for human or animal consumption
Chemical Structure Depiction
Purity	99% Purity
Classification	Research Use Only (RUO), not for human or animal consumption
Storage Temperature	Long-term (up to 6 months): Store at -80°C (-112°F) Short-term (up to 1 month): Store at -20°C (-4°F)

Mechanisms of Action

In experimental studies, ACP-105 has been characterized as a selective androgen receptor (AR) agonist with partial agonistic activity relative to endogenous androgens.

Laboratory investigations suggest the compound may:

• Interact with androgen receptor signaling pathways
• Demonstrate selective receptor binding characteristics
• Exhibit partial agonist activity in receptor-mediated signaling assays

Some experimental data also indicate that ACP-105 may cross the blood-brain barrier in animal models, allowing researchers to examine its interaction with androgen receptors within central nervous system tissues.

Potential Research Applications

Several preclinical and animal-based investigations have examined ACP-105 to better understand its receptor selectivity and biological signaling activity.

In laboratory studies, ACP-105 has been observed to:

• Selectively interact with androgen receptors
• Demonstrate limited interaction with other hormone receptor systems in experimental assays
• Produce measurable biological responses in androgen-responsive tissues within animal models

Because current research primarily involves preclinical models, further controlled investigations are necessary to fully characterize its receptor activity, signaling pathways, and broader biological interactions.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use

References:

1. George, S., Petit, G. H., Gouras, G. K., Brundin, P., & Olsson, R. (2013). Nonsteroidal Selective Androgen Receptor Modulators and Selective Estrogen Receptor β Agonists Moderate Cognitive Deficits and Amyloid-β Levels in a Mouse Model of Alzheimer’s Disease. ACS Chemical Neuroscience, 4(12), 1537-1548. https://doi.org/10.1021/cn400133s
2. Schlienger, N., Lund, B. W., Pawlas, J., Badalassi, F., Bertozzi, F., Lewinsky, R., Fejzic, A., Thygesen, M. B., Tabatabaei, A., Bradley, S. R., Gardell, L. R., Piu, F., & Olsson, R. (2009). Synthesis, Structure-Activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators. Journal of Medicinal Chemistry, 52(22), 7186-7191. https://doi.org/10.1021/jm901149c
3. Dayger, C., Villasana, L., Pfankuch, T., Davis, M., & Raber, J. (2011). Effects of the SARM ACP-105 on rotorod performance and cued fear conditioning in sham-irradiated and irradiated female mice. Brain Research, 1381, 134-140. https://doi.org/10.1016/j.brainres.2010.12.088

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All products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use.